m****g 发帖数: 118 | 1 【 以下文字转载自 Medicine 讨论区 】
发信人: mazing (明天会更好), 信区: Medicine
标 题: 求助:脑血栓!!!
发信站: BBS 未名空间站 (Sun Jun 30 10:29:40 2013, 美东)
病人是朋友的父亲,人在国内,抢救了几天还处于基本昏迷状态:
男性,68岁,大面积的脑血管梗塞(脑血栓),6月21日凌晨1点多发病,当时左半侧无
法移动,后经120急救送至医院,3点钟左右开始输液,接近5点钟开始静脉注射70mg阿
替普酶alteplase(强溶栓剂),但是没有溶开。后脑内出现大面积水肿,至23日中午
基本昏迷,(前两天神志还清醒,只是晕晕乎乎,还能吃些东西,能认人,能说话)昏
迷时右侧瞳孔有放大迹象,立即进行了开颅去骨瓣手术(右侧脑骨,去掉一大块,这样
能让水肿有地方扩大,减少颅内压力),术后瞳孔有回复迹象,但因为水肿仍处在高峰
期,颅内压力依然很大,而且持续上升,所以,瞳孔又进一步扩散。
至今高峰期已过,但水肿削减要有个过程,所以,脑干始终处于被挤压状态, 最担心的
是对脑干破坏时间越长越难恢复。现在病人未苏醒,但瞳孔趋向正常,肺部开始有感染
、发烧,心脏房颤持续有发生,这些医生都在治疗。
现在最担心的就是:即使包括心脏、肺这些并发症都能闯过去,大脑脑干有没有办法恢
复?如果恢复不了,就可能成植物人...
请问:
是否从现在开始能有些什么更好的措施和药物,尽可能的使脑干受损减少,恢复加速?
(目前这边始终使用的是大剂量的甘露醇和人血白蛋白)
另外,美国这边有没有比国内先进的治疗手段/方式?
感谢提供任何相关信息/建议!!! |
A*******s 发帖数: 9638 | 2 听上去不太好,该做的都做了,脑损伤包括脑干损伤都已经发生了,现在的治疗只是减
少进一步损伤。 预后只有时间能够告诉你了。 Bless
For teaching purposes, if a patient like this develops a right sided
weakness. what do you call it? |
d**o 发帖数: 618 | 3
Ipsilateral medulla compression because of brain herniation?
【在 A*******s 的大作中提到】 : 听上去不太好,该做的都做了,脑损伤包括脑干损伤都已经发生了,现在的治疗只是减 : 少进一步损伤。 预后只有时间能够告诉你了。 Bless : For teaching purposes, if a patient like this develops a right sided : weakness. what do you call it?
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A*******s 发帖数: 9638 | 4 Nope.
【在 d**o 的大作中提到】 : : Ipsilateral medulla compression because of brain herniation?
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D******D 发帖数: 1159 | 5 It's on FA:
Uncal herniation:
Compression of contralateral crus cerebri (Kernohan's notch) |
A*******s 发帖数: 9638 | 6 Bingo.
【在 D******D 的大作中提到】 : It's on FA: : Uncal herniation: : Compression of contralateral crus cerebri (Kernohan's notch)
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A*******s 发帖数: 9638 | 7 Can anyone tell LZ what is the difference of treatment between US and China
for a case like this? |
d**o 发帖数: 618 | 8 哇,不查不知,一查吓一跳,uncal herniation在FA12里是八行的一个section,在
FA13里删得只剩一句话了,可怜我一直只看FA13。看来要追高分,一定得看好几个FA版
本才行
【在 D******D 的大作中提到】 : It's on FA: : Uncal herniation: : Compression of contralateral crus cerebri (Kernohan's notch)
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A*******s 发帖数: 9638 | 9 You can save youself if you can tell LZ what we do here for a case like that
. :)
【在 d**o 的大作中提到】 : 哇,不查不知,一查吓一跳,uncal herniation在FA12里是八行的一个section,在 : FA13里删得只剩一句话了,可怜我一直只看FA13。看来要追高分,一定得看好几个FA版 : 本才行
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A*******s 发帖数: 9638 | 10 By no means I intended to make any comments on the treatment by our fellow
chinese physicians. Instead, I just try to clarify some points on the
treatment of stroke in the US for our Externs.
1. TPA probably is not going to work for such a large stroke, what is the
alternative treatment?
2. What do you think about the craniotomy?
【在 d**o 的大作中提到】 : 哇,不查不知,一查吓一跳,uncal herniation在FA12里是八行的一个section,在 : FA13里删得只剩一句话了,可怜我一直只看FA13。看来要追高分,一定得看好几个FA版 : 本才行
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d**o 发帖数: 618 | 11 I'm not sure what are the points you try to clarify.
1. At this point there is no alternative that is proven better than tPA.
http://www.medscape.com/viewarticle/778998
2. You may say the pt is a little too old for hemicraniectomy, but it is not
excessive.
"Patients with malignant MCA territory infarction should be enrolled in
randomized controlled trials of decompressive hemicraniectomy if this option
is available. In the absence of clinical trial availability, and given the
dire prognosis associated with medical treatment, we suggest decompressive
hemicraniectomy for patients age 50 or younger with an indisputable
diagnosis of malignant middle cerebral artery territory infarction (with >50
percent infarction of MCA territory by head CT) who are at high risk of
developing malignant edema and who desire aggressive therapy. This surgery
may also be offered on a case-by-case basis for otherwise healthy patients
older than 50 and beyond 48 hours after stroke onset." - uptodate
【在 A*******s 的大作中提到】 : By no means I intended to make any comments on the treatment by our fellow : chinese physicians. Instead, I just try to clarify some points on the : treatment of stroke in the US for our Externs. : 1. TPA probably is not going to work for such a large stroke, what is the : alternative treatment? : 2. What do you think about the craniotomy?
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A*******s 发帖数: 9638 | 12 I have to stop here. Questions I raised are just for teaching purpose. You
will learn what alternative treatment is and what is excessive in your later
clinical practice.
not
option
the
【在 d**o 的大作中提到】 : I'm not sure what are the points you try to clarify. : 1. At this point there is no alternative that is proven better than tPA. : http://www.medscape.com/viewarticle/778998 : 2. You may say the pt is a little too old for hemicraniectomy, but it is not : excessive. : "Patients with malignant MCA territory infarction should be enrolled in : randomized controlled trials of decompressive hemicraniectomy if this option : is available. In the absence of clinical trial availability, and given the : dire prognosis associated with medical treatment, we suggest decompressive : hemicraniectomy for patients age 50 or younger with an indisputable
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m****g 发帖数: 118 | 13 谢谢答复!请问tPA 是什么呀? MRA 是指 MRI 么?做 MRA 目的是?(病人有做CT)
【在 d**o 的大作中提到】 : I'm not sure what are the points you try to clarify. : 1. At this point there is no alternative that is proven better than tPA. : http://www.medscape.com/viewarticle/778998 : 2. You may say the pt is a little too old for hemicraniectomy, but it is not : excessive. : "Patients with malignant MCA territory infarction should be enrolled in : randomized controlled trials of decompressive hemicraniectomy if this option : is available. In the absence of clinical trial availability, and given the : dire prognosis associated with medical treatment, we suggest decompressive : hemicraniectomy for patients age 50 or younger with an indisputable
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d**o 发帖数: 618 | 14 sorry for the confusion, 那个回复只是跟Aplusplus讨论用的,跟您这个病例关系不
大,我已经删了
tPA就是alteplase. 做MRA(是一种MRI)并不是必须的标准程序.
【在 m****g 的大作中提到】 : 谢谢答复!请问tPA 是什么呀? MRA 是指 MRI 么?做 MRA 目的是?(病人有做CT)
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z*****2 发帖数: 498 | 15 在国内时我们曾对一些急性出血性stroke积极手术,救了很多人的命,
但基本成植物人或预后很差。来美进修感觉他们很不积极,讨论起来
他们讲没有生活的quality,所以不积极。当时我非常shock,因为我们
国内不会因为life quality不好而放弃救命。 |
m******h 发帖数: 297 | 16 理念不一样,西方因为宗教的关系,不认为死亡意味着一切的结束,所以注重生活的质
量。而中国人认为死了就是到此为止,其他的什么也别谈了,只要“活着”就留的青山
在。
【在 z*****2 的大作中提到】 : 在国内时我们曾对一些急性出血性stroke积极手术,救了很多人的命, : 但基本成植物人或预后很差。来美进修感觉他们很不积极,讨论起来 : 他们讲没有生活的quality,所以不积极。当时我非常shock,因为我们 : 国内不会因为life quality不好而放弃救命。
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c*****r 发帖数: 50 | 17 到这个点上,在美国也没有其它办法。不要输液太多造成更多水肿,只是觉得中国溶栓
速度太幔。只能听天由命,穑幋过右侧大脑中风,预后比左侧相对好一些。
【在 m****g 的大作中提到】 : 【 以下文字转载自 Medicine 讨论区 】 : 发信人: mazing (明天会更好), 信区: Medicine : 标 题: 求助:脑血栓!!! : 发信站: BBS 未名空间站 (Sun Jun 30 10:29:40 2013, 美东) : 病人是朋友的父亲,人在国内,抢救了几天还处于基本昏迷状态: : 男性,68岁,大面积的脑血管梗塞(脑血栓),6月21日凌晨1点多发病,当时左半侧无 : 法移动,后经120急救送至医院,3点钟左右开始输液,接近5点钟开始静脉注射70mg阿 : 替普酶alteplase(强溶栓剂),但是没有溶开。后脑内出现大面积水肿,至23日中午 : 基本昏迷,(前两天神志还清醒,只是晕晕乎乎,还能吃些东西,能认人,能说话)昏 : 迷时右侧瞳孔有放大迹象,立即进行了开颅去骨瓣手术(右侧脑骨,去掉一大块,这样
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